Is it All in your head?
Maybe not! Maybe it’s in your genes. Maybe you got that fear of heights from your great-grandfather you never met. That fear of spiders from your grandmother. And maybe that tendency to addiction as well. What? Yup, sounds crazy until you read the epigenetic article published in Nature Neuroscience magazine last December.
Epigenetic refers to chemical changes that affect gene expression without changing your DNA. According to the epigenetic study conducted by neurobiologists at Emory University in Atlanta, mouse pups and even their offspring’s offspring can inherit a fearful association of a certain smell with pain; even if they have not experienced the pain themselves, and even without the need for genetic mutations. The scientists are talking about a subject that’s extremely controversial and fascinating. The question here is, Can certain fears be inherited down through the generations. The answer produced by the well-thought-out study is yes!
Here’s how the experiment went. Lab mice were exposed to a certain smell they’d never been exposed to before and at the same time given a mild unpleasant electrical stimulus to their feet. Over time, the mice developed anxious behavior in response to the smell and the impending electrical stimulus. These mice were then allowed to breed and the first-generation mice (children) were then exposed to the same smell without the electrical stimulus. These mice displayed the exact same anxious behavior their parents did. The fear had been transferred to the next generation. The first-generation mice when mature, were allowed to breed, and then the second-generation mice (grandchildren) were also exposed to the smell without the electrical stimulus. The grandchildren also displayed the exact same anxious behavior of the parents and grandparents. The implication here is that experience affects gene expression, and this experience is handed down through generations.
The neurobiologist who co-authored the study became interested in epigenetic inheritance after working with poor people living in inner cities, where cycles of drug addiction, neuropsychiatric illness and other problems often seem to recur in parents and their children. He states, “There are a lot of anecdotes to suggest that there’s intergenerational transfer of risk, and that it’s hard to break the cycle.”
You can be sure there will be more studies in the future, and in the meantime, it might be wise for all of us to have even more compassion for those who struggle with anxiety or addictions.
Yours in health,
Dr. Grondin
Maybe not! Maybe it’s in your genes. Maybe you got that fear of heights from your great-grandfather you never met. That fear of spiders from your grandmother. And maybe that tendency to addiction as well. What? Yup, sounds crazy until you read the epigenetic article published in Nature Neuroscience magazine last December.
Epigenetic refers to chemical changes that affect gene expression without changing your DNA. According to the epigenetic study conducted by neurobiologists at Emory University in Atlanta, mouse pups and even their offspring’s offspring can inherit a fearful association of a certain smell with pain; even if they have not experienced the pain themselves, and even without the need for genetic mutations. The scientists are talking about a subject that’s extremely controversial and fascinating. The question here is, Can certain fears be inherited down through the generations. The answer produced by the well-thought-out study is yes!
Here’s how the experiment went. Lab mice were exposed to a certain smell they’d never been exposed to before and at the same time given a mild unpleasant electrical stimulus to their feet. Over time, the mice developed anxious behavior in response to the smell and the impending electrical stimulus. These mice were then allowed to breed and the first-generation mice (children) were then exposed to the same smell without the electrical stimulus. These mice displayed the exact same anxious behavior their parents did. The fear had been transferred to the next generation. The first-generation mice when mature, were allowed to breed, and then the second-generation mice (grandchildren) were also exposed to the smell without the electrical stimulus. The grandchildren also displayed the exact same anxious behavior of the parents and grandparents. The implication here is that experience affects gene expression, and this experience is handed down through generations.
The neurobiologist who co-authored the study became interested in epigenetic inheritance after working with poor people living in inner cities, where cycles of drug addiction, neuropsychiatric illness and other problems often seem to recur in parents and their children. He states, “There are a lot of anecdotes to suggest that there’s intergenerational transfer of risk, and that it’s hard to break the cycle.”
You can be sure there will be more studies in the future, and in the meantime, it might be wise for all of us to have even more compassion for those who struggle with anxiety or addictions.
Yours in health,
Dr. Grondin